Arnaldo Rizzo, MD – Morphodynamic Cosmetic Surgery Abstract Recent discoveries in mechanobiology, particularly the work of Li et al. (2025), have revealed that direct cell-to-cell contact can induce fibroblast-to-myofibroblast transition independently of traditional biochemical or extracellular mechanical cues. This finding redefines fibrosis as a mechanical and communicative dysfunction, rather than merely an inflammatory or biochemical event. Understanding this mechanism provides… Leggi di più... "Mechanobiological Strategies for Fibrosis Control: From Cellular Contact to Functional Morphodynamic"
Bone atrophy caused by facial onlay implants.
The aim of this article is to explore the medium- to long-term consequences of onlay-type facial prosthesis applications. The rationale is that inserting a prosthesis, made of any material, eliminates the physiological mechanical stimulation of muscles and neuromuscular dynamics, leading to negative remodeling of the bones on which the prosthesis is placed. Leggi di più... "Bone atrophy caused by facial onlay implants."
Effects of linear scars on the face
Facial inear scars, according to one Morphodynamic perspective, can be considered “Distant Modulators of Facial Dynamics”. Linear scars are not only localized cutaneous alterations, but persistent biomechanical factors capable of influencing tissues beyond their anatomical borders (Tomasek et al. 2002; Gurtner et al. 2008). The anisotropic deposition of collagen generates mechanical discontinuities that alter local tension fields, with consequences that… Leggi di più... "Effects of linear scars on the face"
Update on Xerostomia and Dry eyes Syndrome.
Introduction Oral and ocular dryness are frequent consequences of autoimmune diseases such as Sjögren’s syndrome, endocrinological pathologies, head and neck radiotherapy and age related atrophy. Conventional therapies are mainly symptomatic. In recent years, however, regenerative approaches based on PRP, stem cells, exosomes, tissue engineering and mechanobiology have emerged as promising alternatives. Platelet-Rich Plasma (PRP) PRP, through the release of growth… Leggi di più... "Update on Xerostomia and Dry eyes Syndrome."