The aim of this article is to explore the medium- to long-term consequences of onlay-type facial prosthesis applications. The rationale is that inserting a prosthesis, made of any material, eliminates the physiological mechanical stimulation of muscles and neuromuscular dynamics, leading to negative remodeling of the bones on which the prosthesis is placed. Leggi di più... "Bone atrophy caused by facial onlay implants."
Update on Xerostomia and Dry eyes Syndrome.
Introduction Oral and ocular dryness are frequent consequences of autoimmune diseases such as Sjögren’s syndrome, endocrinological pathologies, head and neck radiotherapy and age related atrophy. Conventional therapies are mainly symptomatic. In recent years, however, regenerative approaches based on PRP, stem cells, exosomes, tissue engineering and mechanobiology have emerged as promising alternatives. Platelet-Rich Plasma (PRP) PRP, through the release of growth… Leggi di più... "Update on Xerostomia and Dry eyes Syndrome."
Xerostomia e sindrome dell’occhio secco (approfondimento).
Introduzione La secchezza orale (xerostomia) e la secchezza oculare (dry eye) derivano tipicamente da un’insufficiente funzione delle ghiandole salivari e lacrimali. Cause comuni includono la Sindrome di Sjögren (SS), una malattia autoimmune con infiltrazione linfocitaria nelle ghiandole esocrine, e i danni post-radioterapia (ad esempio in pazienti trattati per tumori testa-collo). Queste condizioni provocano un forte impatto sulla qualità di vita:… Leggi di più... "Xerostomia e sindrome dell’occhio secco (approfondimento)."
Rigenerazione delle ghiandole salivari e lacrimali in caso di secchezza. (Xerostomia e sindrome degli occhi secchi)
La secchezza orale e oculare rappresentano conseguenze frequenti di patologie autoimmuni (come la Sindrome di Sjögren), di patologie endocrine, dei danni post-radioterapia e di atrofia da età o stress. Le strategie terapeutiche tradizionali sono prevalentemente sintomatiche. Negli ultimi anni, tuttavia, sono emerse linee di ricerca rigenerative basate su PRP, cellule staminali, esosomi, ingegneria tissutale e meccano-biologia. Plasma ricco di piastrine… Leggi di più... "Rigenerazione delle ghiandole salivari e lacrimali in caso di secchezza. (Xerostomia e sindrome degli occhi secchi)"
Technique of Morphodynamic Cosmetic Surgery.
Introduction More and more often, minimally invasive surgery is preferred to more aggressive procedures. Various parts of the face and body can be reshaped with Morphodynamic Cosmetic Surgery methods, avoiding the need for invasive operations in later years. Facial Profiloplasty and Harmonization All parts of the face are interconnected: modifying one area produces effects on the others. Morphodynamic Cosmetic Surgery… Leggi di più... "Technique of Morphodynamic Cosmetic Surgery."
The role of Mechanobiology in Regenerative Aesthetic Medicine and Morphodynamic Cosmetic Surgery (MDCS).
Abstract: Different mechanical forces play an important role in all stages of human life, from the embryonic period (morphogenesis) to aging, through the development, maturation and maintenance of organs and tissues. Mechanical stimuli also play a key role in regenerative medicine, as it has been demonstrated that stem cells undergo differentiation under mechanical stimulation. Mechanobiology is the study of how… Leggi di più... "The role of Mechanobiology in Regenerative Aesthetic Medicine and Morphodynamic Cosmetic Surgery (MDCS)."
Stem Cells: The Foundation of Regenerative Medicine.
Stem cells have the unique ability to differentiate and specialize into virtually all types of human cells—around 200 in total—including nerves, skin, muscle, liver, heart, and bone. They are generally classified by origin: Among these, adult stem cells represent a particularly valuable resource thanks to their accessibility and clinical potential. Adult stem cells are pluripotent and can regenerate or replace… Leggi di più... "Stem Cells: The Foundation of Regenerative Medicine."
What About Blepharoplasty?
Blepharoplasty is one of the most frequently performed cosmetic surgeries—but also one of the procedures with the highest rate of long-term patient dissatisfaction. The classic technique involves removing excess skin of the upper eyelid through a spindle-shaped incision, often combined with the removal of periocular fat. For the lower eyelid, surgery typically reduces the “bags” via an incision along the… Leggi di più... "What About Blepharoplasty?"
Shock termico e danno al DNA nei trattamenti con radiofrequenza
I dispositivi a radiofrequenza (RF) riscaldano intenzionalmente i tessuti dermici e sottocutanei per indurre denaturazione del collagene e neocollagenesi. Sebbene la maggior parte dei sistemi sia progettata per proteggere l’epidermide, l’energia erogata porta spesso la temperatura intradermica oltre i 45 °C, soglia alla quale sono stati documentati shock termico ed effetti genotossici. A 42–45 °C, le cellule attivano le proteine… Leggi di più... "Shock termico e danno al DNA nei trattamenti con radiofrequenza"
Meccanobiologia: spunti bibliografici di rilievo.
Mechanical regulation of bone remodeling. Wang L Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic mechanical forces, altering bone mass in response to changing conditions. Mechanical forces are indispensable for bone… Leggi di più... "Meccanobiologia: spunti bibliografici di rilievo."