Abstract Facial bone morphology has traditionally been attributed to genetic and developmental factors. There are numerous scientific publications that highlight the role of the masticatory muscles in determining the development and evolution of the jaw bones, but very few publications mention the role of the non-masticatory muscles in shaping the facial bones during development and after maturity. However, increasing evidence… Leggi di più... "Facial Bone Morphology Modulated by Masticatory and Non‑Masticatory Muscular Activity: Evidence for Morphodynamic Cosmetic Surgery. Rizzo A."
Mechanobiological Strategies for Fibrosis Control: From Cellular Contact to Functional Morphodynamic
Arnaldo Rizzo, MD – Morphodynamic Cosmetic Surgery Abstract Recent discoveries in mechanobiology, particularly the work of Li et al. (2025), have revealed that direct cell-to-cell contact can induce fibroblast-to-myofibroblast transition independently of traditional biochemical or extracellular mechanical cues. This finding redefines fibrosis as a mechanical and communicative dysfunction, rather than merely an inflammatory or biochemical event. Understanding this mechanism provides… Leggi di più... "Mechanobiological Strategies for Fibrosis Control: From Cellular Contact to Functional Morphodynamic"
Mechanobiomaterials: Integrating Mechanics and Biology for Tissue Regeneration
Definition and Concept The term “mechanobiomaterials” was proposed to describe biomaterials designed to engage with living tissues through mechanical interactions rather than passive biochemical compatibility (Lin et al., 2024, Sui et al., 2024), a new class of biomaterials designed to actively engage mechanobiological principles to enhance tissue regeneration. The authors discussed how materials can be engineered to deliver mechanical cues—such… Leggi di più... "Mechanobiomaterials: Integrating Mechanics and Biology for Tissue Regeneration"
New paradigms in MYOMODULATION of facial Dynamics.
The fundamental principle of Morphodynamic Cosmetic Surgery is that “function determines form,” according to the 1997 “Moss Functional Matrix” theory (Rizzo 2020). In recent years, the emerging discipline of Mechanobiology has explored the mechanisms of action of extrinsic mechanical stimuli, explaining in detail how cells, tissues, and organs translate mechanical stimuli into biological processes (https://www.chirurgiacosmeticamorfodinamica.it/2025/10/21/the-role-of-mechanobiology-in-regenerative-aesthetic-medicine-and-morphodynamica-cosmetic-surgery-mdcs/) Leggi di più... "New paradigms in MYOMODULATION of facial Dynamics."
Bone atrophy caused by facial onlay implants.
The aim of this article is to explore the medium- to long-term consequences of onlay-type facial prosthesis applications. The rationale is that inserting a prosthesis, made of any material, eliminates the physiological mechanical stimulation of muscles and neuromuscular dynamics, leading to negative remodeling of the bones on which the prosthesis is placed. Leggi di più... "Bone atrophy caused by facial onlay implants."
Effects of linear scars on the face
Facial inear scars, according to one Morphodynamic perspective, can be considered “Distant Modulators of Facial Dynamics”. Linear scars are not only localized cutaneous alterations, but persistent biomechanical factors capable of influencing tissues beyond their anatomical borders (Tomasek et al. 2002; Gurtner et al. 2008). The anisotropic deposition of collagen generates mechanical discontinuities that alter local tension fields, with consequences that… Leggi di più... "Effects of linear scars on the face"
Update on Xerostomia and Dry eyes Syndrome.
Introduction Oral and ocular dryness are frequent consequences of autoimmune diseases such as Sjögren’s syndrome, endocrinological pathologies, head and neck radiotherapy and age related atrophy. Conventional therapies are mainly symptomatic. In recent years, however, regenerative approaches based on PRP, stem cells, exosomes, tissue engineering and mechanobiology have emerged as promising alternatives. Platelet-Rich Plasma (PRP) PRP, through the release of growth… Leggi di più... "Update on Xerostomia and Dry eyes Syndrome."
Xerostomia e sindrome dell’occhio secco (approfondimento).
Introduzione La secchezza orale (xerostomia) e la secchezza oculare (dry eye) derivano tipicamente da un’insufficiente funzione delle ghiandole salivari e lacrimali. Cause comuni includono la Sindrome di Sjögren (SS), una malattia autoimmune con infiltrazione linfocitaria nelle ghiandole esocrine, e i danni post-radioterapia (ad esempio in pazienti trattati per tumori testa-collo). Queste condizioni provocano un forte impatto sulla qualità di vita:… Leggi di più... "Xerostomia e sindrome dell’occhio secco (approfondimento)."
Rigenerazione delle ghiandole salivari e lacrimali in caso di secchezza. (Xerostomia e sindrome degli occhi secchi)
La secchezza orale e oculare rappresentano conseguenze frequenti di patologie autoimmuni (come la Sindrome di Sjögren), di patologie endocrine, dei danni post-radioterapia e di atrofia da età o stress. Le strategie terapeutiche tradizionali sono prevalentemente sintomatiche. Negli ultimi anni, tuttavia, sono emerse linee di ricerca rigenerative basate su PRP, cellule staminali, esosomi, ingegneria tissutale e meccano-biologia. Plasma ricco di piastrine… Leggi di più... "Rigenerazione delle ghiandole salivari e lacrimali in caso di secchezza. (Xerostomia e sindrome degli occhi secchi)"
Technique of Morphodynamic Cosmetic Surgery.
Introduction More and more often, minimally invasive surgery is preferred to more aggressive procedures. Various parts of the face and body can be reshaped with Morphodynamic Cosmetic Surgery methods, avoiding the need for invasive operations in later years. Facial Profiloplasty and Harmonization All parts of the face are interconnected: modifying one area produces effects on the others. Morphodynamic Cosmetic Surgery… Leggi di più... "Technique of Morphodynamic Cosmetic Surgery."